•  Any factor that interferes with the functioning of the immune system will slow down the process of tattoo clearing and result in more treatments will be needed.
  •  Medical conditions include Diabetes Mellitus, cancer, patients on chemotherapy, patients on steroids, and on medications for chronic arthritis and autoimmune conditions.
  •  Smoking has significant effects, not only on the immune system but also on the cardiovascular system, especially on the microcirculation to tissues.